Hydrocortisone Cream belongs to a group of medicines named topical cortiscosteroids that work by calming inflammation that occurs from skin conditions and reactions. In order to calm the inflammation, the cream alters the body’s responses to inflammatory reactions, therefore reducing swelling, redness and itching. Hydrocortisone Cream 1% alleviates itching and irritation for up to 12 hours and promotes the healing of : insect bites mild to moderate eczema detergent hands nickel allergies plant allergies makeup allergies strong detergent chemical reactions dermatitis eczema poison ivy poison oak Hydrocortisone cream is usually used one to four times a day for treating skin problems. It may be prescribed for treating other conditions or uses. For more information, contact your local pharmacist.